BDBM50200975 CHEMBL3916621::US10087187, Compound 2

SMILES Cc1c(Cc2c(CNCCS(C)(=O)=O)nc3c(N)cc(nn23)N2CCOCC2)cccc1C(F)(F)F

InChI Key InChIKey=GWFUHMDGIDDKAR-UHFFFAOYSA-N

Data  2 IC50  10 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50200975   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50200975(CHEMBL3916621 | US10087187, Compound 2)
Affinity DataKd:  8.13E+3nMAssay Description:Binding affinity to human PI3Kalpha (108 to 1068 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed